TY - CHAP M1 - Book, Section TI - Chapter 95. Malaria A1 - Cline, David M. A2 - Cline, David M. A2 - Ma, O. John A2 - Cydulka, Rita K. A2 - Meckler, Garth D. A2 - Handel, Daniel A. A2 - Thomas, Stephen H. PY - 2012 T2 - Tintinalli's Emergency Medicine Manual, 7e AB - Malaria must be considered in any person who has traveled to the tropics and presents with an unexplained febrile illness. Five species of the protozoan Plasmodium infect humans: P falciparum, P vivax, P ovale, P malariae, and P knowlesi. The organism is transmitted by the anopheline mosquito bite and travels hematogenously first to the liver, where asexual reproduction occurs (exoerythrocytic stage). The liver cell ruptures, releasing merozoites that invade erythrocytes, multiply, and cause hemolysis (erythrocytic stage). Malaria also may be transmitted by blood transfusion or passed transplacentally from mother to fetus. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=56275380 ER -