RT Book, Section A1 Huff, J. Stephen A2 Tintinalli, Judith E. A2 Stapczynski, J. Stephan A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Cline, David M. SR Print(0) ID 1121511795 T1 Altered Mental Status and Coma T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071794763 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1121511795 RD 2024/04/20 AB Disorders of consciousness may be divided into processes that affect either arousal or content of consciousness, or a combination of both. Arousal behaviors include wakefulness and basic alerting. Anatomically, neurons responsible for these arousal functions reside in the reticular activating system, a collection of neurons scattered through the midbrain, pons, and medulla. The neuronal structures responsible for the content of consciousness reside in the cerebral cortex. Content of consciousness includes self-awareness, language, reasoning, spatial relationship integration, emotions, and the myriad complex integration processes that make us human. One simplistic model holds that dementia is failure of the content portions of consciousness with relatively preserved alerting functions. Delirium is arousal system dysfunction with the content of consciousness affected as well. Coma is failure of both arousal and content functions. Psychiatric disorders and altered mental states may share features such as hallucinations or delusion. Some distinctions between the different states are summarized in Table 168-1.