RT Book, Section A1 Casey, Glass A1 David, Manthey A2 Tintinalli, Judith E. A2 Stapczynski, J. Stephan A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Cline, David M. SR Print(0) ID 1121520664 T1 Cardiogenic Shock T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071794763 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1121520664 RD 2024/04/23 AB Cardiogenic shock is an acute state of decreased cardiac output resulting in inadequate tissue perfusion despite adequate circulating volume. Cardiogenic shock is the leading cause of in-hospital death in patients with acute myocardial infarction (AMI).1 The true incidence of cardiogenic shock is unknown because many patients die before arrival and escape estimates. Cardiogenic shock is seen in 4% to 8% of patients with ST-segment elevation myocardial infarction (STEMI).2,3 The incidence is declining in part as a result of the increased use of percutaneous intervention for AMI.3,4,5,6 Cardiogenic shock occurs less frequently (2.5%) in those with non–ST-segment elevation myocardial infarction (NSTEMI) compared with those with STEMI.7,8 Only ~10% of AMI patients who will develop cardiogenic shock have it at ED presentation, with the median time of onset after arrival being approximately 6 hours.2,9 This underscores the therapeutic opportunity that exists by thwarting ongoing myocardial ischemia.