RT Book, Section
A1 Kalb, Thomas H.
A1 Frontera, Jennifer A.
A2 Farcy, David A.
A2 Chiu, William C.
A2 Flaxman, Alex
A2 Marshall, John P.
SR Print(0)
ID 55812328
T1 Chapter 20. Acute Liver Failure: How to Orchestrating Emergency Critical Care Interventions
T2 Critical Care Emergency Medicine
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-162824-2
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=55812328
RD 2024/04/23
AB A  patient  who  presents  emergently  with  acute  liver  failure  (ALF)  has  an  overall  greater  likelihood  of  either  dying  or  requiring  emergent  transplantation  than  recovering  without  transplant.1  Regardless  of  etiology,  the  unifying  feature  of  ALF  is  a  compact  clinical  timeline  and  a  rapid,  often  precipitous  natural  history  of  disease.  Whereas  spontaneous  recovery  of  liver  function  is  possible  with  supportive  measures,  particularly  with  acetaminophen  overdose,  there  remains  a  significant  risk  of  spiraling  decline  after  presentation  with  multiorgan  failure,  bleeding,  and  infectious  complications  often  heralded  by  high-grade  encephalopathy  with  cerebral  edema.2