RT Book, Section
A1 Farcy, David A.
A1 Yashou, John
A1 Rivers, Emanuel
A2 Farcy, David A.
A2 Chiu, William C.
A2 Flaxman, Alex
A2 Marshall, John P.
SR Print(0)
ID 55814275
T1 Chapter 36. Sepsis and Septic Shock
T2 Critical Care Emergency Medicine
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-162824-2
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=55814275
RD 2024/04/19
AB Of  the  120  million  patients  presenting  to  the  emergency  department  (ED)  in  the  United  States  per  year,  2.9%  or  over  600,000  carry  a  diagnosis  of  severe  sepsis  and  septic  shock  in  the  United  States.  The  overall  hospital  mortality  for  sepsis,  severe  sepsis,  and  septic  shock  is  15%,  20%,  and  45%,  respectively.  Sepsis  is  responsible  for  9%  of  the  deaths  or  210,000  deaths  per  year  in  the  United  States.  By  comparison,  180,000  persons  die  of  acute  myocardial  infarction  and  200,000  die  of  lung  or  breast  cancer  annually.  Many  patients  with  severe  sepsis  and  septic  shock  present  to  the  ED  where  there  are  often  long  delays  before  transfer  to  an  intensive  care  unit  (ICU)  bed.  Sepsis  is  the  most  expensive  diagnosis  admitted  to  hospitals  accounting  for  over  $50  billion  in  health  care  costs  each  year.  It  is  because  of  these  aforementioned  factors  that  the  ED  has  become  a  logical  focal  point  for  sepsis  diagnosis  and  treatment.  It  is  during  the  first  6  hours  that  sepsis  management  can  improve  outcomes  in  one  of  every  six  patients  who  present  with  the  disease.1