RT Book, Section A1 Reichman, Eric F. SR Print(0) ID 57703847 T1 Chapter 37. Intracardiac Injection T2 Emergency Medicine Procedures, 2e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-161352-1 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=57703847 RD 2024/04/19 AB The practice of intracardiac injection originated in the 1800s. It was quite commonly performed throughout the 1960s, as it was thought to be the most expeditious route of drug delivery during a cardiac arrest.1,2 By the mid-1970s, the practice of intracardiac injection declined. Safer and simpler routes of medication administration (i.e., intravenous, endotracheal, and intraosseous) became available. Experimental data suggested that there was no advantage to intracardiac injection over intravenous administration of medications. Cardiopulmonary resuscitation (CPR) must be interrupted to perform an intracardiac injection. In difficult patients or in inexperienced hands, the time required for this procedure may be too prolonged. Finally, many serious complications may occur as a result of an intracardiac injection.2