RT Book, Section A1 Aks, Steven E. A2 Sherman, Scott C. A2 Weber, Joseph M. A2 Schindlbeck, Michael A. A2 Rahul G., Patwari SR Print(0) ID 1101225885 T1 Salicylate Toxicity T2 Clinical Emergency Medicine YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-179460-2 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1101225885 RD 2024/04/24 AB Salicylate toxicity causes a mixed respiratory alkalosis, metabolic alkalosis, and elevated anion gap metabolic acidosis.Chronically intoxicated patients will be more seriously ill at lower salicylate concentrations than their acutely poisoned counterparts.Pursue hemodialysis in patients with refractory acidosis, pulmonary edema, renal insufficiency, and altered mental status or seizure, regardless of the actual serum salicylate level.Match the ventilation rate in intubated patients with severe salicylate poisoning to their pre–intubation minute ventilation, as most require remarkably high rates for adequate respiratory compensation.