RT Book, Section A1 Stork, Christine M. A2 Hoffman, Robert S. A2 Howland, Mary Ann A2 Lewin, Neal A. A2 Nelson, Lewis S. A2 Goldfrank, Lewis R. SR Print(0) ID 1108430271 T1 Antibacterials, Antifungals, and Antivirals T2 Goldfrank's Toxicologic Emergencies, 10e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071801843 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1108430271 RD 2024/04/19 AB Antimicrobials, including antibacterials, antifungals, and antivirals, have significantly improved the clinical care of infected patients since the introduction of penicillin in the 1940s. The development of antimicrobial-resistant strains of these pathogens has continually expanded the number of antimicrobials necessary, and this has increased the overall potential for toxicity after use. Fortunately, toxicity due to acute overdose is limited and chronic therapeutic doses are safe in the majority of patients.