RT Book, Section A1 Kecskes, Susan A. A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105684281 T1 Hypo- and Hypernatremia Abnormalities T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1105684281 RD 2024/04/24 AB Sodium concentration reflects both the sodium and water contents of the body.Antidiuretic hormone (ADH) is one of the primary regulatory hormones for sodium concentration. It responds to the changes in osmolality and intravascular volume to restore homeostasis to the body.Hypernatremia may result from: Primary sodium excessHypovolemic hypernatremiaHypernatremia should generally be corrected gradually to avoid the complication of cerebral edema.Aggressive treatment of hyponatremia may lead to the osmotic demyelination syndrome.