How many hours after a cardiac ischemia event would one expect to reliably find a positive troponin?
Troponins leak out of damaged myocardium cells after prolonged ischemia. Thus, it takes 6 hours for cellular death and breakdown for these biomarkers to leak into the bloodstream. Myoglobin elevations may be seen earlier (in the 2–4 hours range). Patients who present soon after symptoms may have NO elevation in biomarkers.