If a patient is potentially dangerous, but not in need of immediate restraint, a psychiatric interview should take place in an open area with nearby security personnel. The physician should begin with an introduction and express the desire to help the patient. If sedation is necessary, haloperidol is the most widely used drug rapid tranquilization, although the recently approved atypical antipsychotics ziprasidone can be an alternative. Many physicians also use droperidol, but the FDA has now issued a warning against the use of this drug based on reports of adverse cardiovascular events including cardiac arrest and torsade de pointes. Lorazepam and other benzodiazepines may be used as adjuncts to neuroleptics for rapid tranquilization. For violent patients, temporary use of physical restraints may be necessary while rapid tranquilization is initiated.