Question 2 of 19

The most common manifestation of Lyme disease is:

Erythema migrans.


Cognitive impairment.

Recurrent arthritis.

Heart block

Lyme disease is caused by the spirochete Borrelia burgdorferi. After B. burgdorferi is introduced into the skin, it spreads locally. The local spread leads to erythema migrans (EM), a rash that is found in approximately two-thirds of patients. Keep in mind that a rash may not be present in up to 20% of cases and even if present may be mild, nonspecific, and easily missed by the patient, family, caregivers, and/or the initial treating physicians.