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Zoonotic infections are a class of specific diseases and infections that are naturally transmitted between vertebrate animals and humans. Transmission may occur via direct contact with an infected animal or animal product, by ingestion of contaminated water or food products, by inhalation, or through arthropod vectors—most commonly ticks. Diagnosis can be challenging because of the nonspecific nature of symptoms (e.g., fever, headache, and myalgias) which overlap with the presentation of many other infectious and autoimmune diseases. Consider zoonotic infections in patients presenting with viral-like illnesses in conjunction with occupational or geographical risk factors for zoonotic disease exposure and transmission. See Table 97-1 for a list of common systemic zoonotic infections and Table 97-2 for specific treatment recommendations for tick-borne diseases.

Table 97-1

Common Systemic Zoonotic Infections

Table 97-2

Tick-borne Zoonotic Infections and Specific Treatment

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