Skip to Main Content

Goldfrank's Toxicologic Emergencies is a multi-authored text of close to 2000 pages prepared by using the education and management principles we apply at the New York City Poison Center and at our clinical sites. In this ninth edition of Goldfrank's Toxicologic Emergencies, we proudly offer readers an approach to medical toxicology using evidence-based principles viewed through a lens of bedside clinical practice. The case history is no longer incorporated in the chapter, but these cases and the critical questions appropriate for discussion are available on the website initially established in the eighth edition. We believe that this supplementary use of the cases recreates a learning environment much like the original text published in 1976 and permits us to use additional text space without creating a heavier, less portable text. In this edition, all the chapters have been revised, and several new chapters have been added. The greatest additions are found in the form of both Antidotes in Depth and Special Considerations, which allow us to address major advances in thought in a highly focused fashion.

Our goal is to assist in understanding new intellectual approaches with an emphasis on the ever-expanding role of medical and clinical toxicologists at the beginning of the twenty-first century. We have continued to increase the number of nationally and internationally known authors who have expertise in their respective areas by reassigning many of the chapters to these experts.

The ninth edition expands on our progress in the eighth edition to use the electronic format. The book has been dramatically improved with the use of full-color graphics and a single art style that will expand and enhance the educational value of the imagery of each chapter and of the image section on the website.

The complete "text" now consists of a hard copy component that offers readers the option of holding while consulting, as they have done previously, as well as an electronic workbook component available on our website (

The workbook, which includes both case studies and annotated multiple-choice questions, is now available on this website and is dramatically enhanced. Many of the cases are relevant classic examples of toxicologic emergencies, and the remainder are new, extensively discussed cases from our regional monthly meetings at the New York City Poison Center. The collective wisdom of many of the current and former text authors continues to guide these sessions as it has for 30 years. Drs. Lewis S. Nelson and Robert S. Hoffman have analyzed these problems, distilled the discussions, and recreated the spirit of these meetings in the printed versions of the cases. Revised annotated multiple-choice questions based on each chapter were developed by the respective chapter authors and edited by Drs. Howard A. Greller and Dean G. Olsen to enhance self-learning and meet the intellectual needs of our readers. Each question has been meticulously meta-tagged by these editors. This allows the learner to sort by a variety of test strategies that are focused on a particular xenobiotic, clinical finding, or therapeutic strategy, to name a few, with the goal of improved individualized learning.

The rewriting and reorganization of this edition of the text has again required an enormous personal effort by each author and the editors as it has in the past, which we hope will facilitate reading, learning, and better patient care. Work on the next edition of this text literally begins the day that the current edition is published because this is such a rapidly evolving field. Although "tearing down" and reconstructing the text between each edition is an extreme exercise, it prevents the editors from accepting and promulgating unfounded treatments and outdated concepts. We hope that you agree that this exercise is worthwhile and that each "new text" continues to serve you well. As always, we encourage your thoughtful comments, and we will do our best, as always, to incorporate your suggestions into future editions.

If this text helps to provide better patient care and stimulates interest in medical toxicology for students of medicine, nursing, and pharmacy and by residents, fellows, and faculty in diverse specialties, our efforts will have indeed been worthwhile.

Lewis S. Nelson
Neal A. Lewin
Mary Ann Howland
Robert S. Hoffman
Lewis R. Goldfrank
Neal E. Flomenbaum

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.