TY - CHAP M1 - Book, Section TI - Acid-Base Disorders A1 - Kelen, Gabor D. A1 - Nicolaou, David D. A1 - Cline, David M. A2 - Tintinalli, Judith E. A2 - Stapczynski, J. Stephan A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Cline, David M. PY - 2016 T2 - Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e AB - Controversy has existed concerning acid-base physiology and the ideal method to assess acid-base disorders for 130 years.1 The two most common methods advocated to analyze acid-base disorders are the traditional bicarbonate-centered method2,3 and the Stewart, or strong ion, method.4,5 The traditional approach teaches that acid-base homeostasis is maintained by respiratory control of the partial pressure of carbon dioxide (Pco2) through changes in alveolar ventilation and control of HCO3– reabsorption and H+ excretion by the kidneys. Peter Stewart proposed that acid-base physiology involves the dynamic interaction of body fluids and multiple chemical species including strong ions (primarily Na+, K+, Ca2+, Mg2+, and Cl–) and weak acids, as well as Pco2 control by the lungs. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1153279612 ER -