TY  - CHAP
M1  - Book, Section
TI  - Chronic Neurologic Disorders
A1  - Handel, Daniel A.
A1  - Gaines, Sarah Andrus
A2  - Tintinalli, Judith E.
A2  - Stapczynski, J. Stephan
A2  - Ma, O. John
A2  - Yealy, Donald M.
A2  - Meckler, Garth D.
A2  - Cline, David M.
PY  - 2016
T2  - Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e
AB  - Amyotrophic  lateral  sclerosis  (ALS),  often  called  Lou  Gehrig's  disease,  causes  rapidly  progressive  muscle  atrophy  and  weakness  resulting  from  the  degeneration  of  both  upper  and  lower  motor  neurons.  ALS  leads  to  varying  degrees  of  spasticity,  hyperreflexia,  and  muscle  paralysis,  eventually  resulting  in  pulmonary  complications  and  the  need  for  mechanical  ventilatory  support.  Because  there  is  no  cure,  clinicians  attempt  to  slow  disease  progression  and  preserve  function  as  much  as  possible.  Medical  management  is  directed  at  preventing  pulmonary  infections  and  forestalling  terminal  respiratory  failure.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessemergencymedicine.mhmedical.com/content.aspx?aid=1132928418
ER  -