TY - CHAP M1 - Book, Section TI - Lithium A1 - Schneider, Sandra M. A1 - Cobaugh, Daniel J. A1 - Kessler, Benjamin D. A2 - Tintinalli, Judith E. A2 - Stapczynski, J. Stephan A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Cline, David M. PY - 2016 T2 - Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e AB - Lithium is one of the most effective medications for the continuous treatment of bipolar disorder. It is particularly useful for the treatment of acute manic episodes and reduces rates of suicide associated with affective disorders.1,2,3 Off-label uses for lithium include augmentation of the action of other antidepressant drugs and treatment of aggression, posttraumatic stress disorder, and pediatric conduct disorders. Lithium for the treatment of Alzheimer's disease is under investigation.4 Lithium toxicity most often results from accidental or intentional overdose, increased dose, or reduction in renal clearance of lithium. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/11 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1132928568 ER -