TY - CHAP M1 - Book, Section TI - Arterial Occlusion A1 - Synovitz, Carolyn K. A2 - Cydulka, Rita K. A2 - Fitch, Michael T. A2 - Joing, Scott A. A2 - Wang, Vincent J. A2 - Cline, David M. A2 - Ma, O. John PY - 2017 T2 - Tintinalli's Emergency Medicine Manual, 8e AB - Peripheral arterial disease is defined as an ankle-brachial index (ABI) of <0.9 (see ABI definition below). The disease prevalence is 4.3% in Americans under age 40 years, and prevalence climbs to 15.5% in those over 70 years of age. High-risk individuals (such as those over 70 years, or those over 50 years with risk factors such as diabetes) should be evaluated carefully when complaints are indicative of possible occlusive arterial disease. Tobacco use significantly increases the risks that an individual will develop peripheral arterial disease. Limb ischemia from an acute arterial occlusion can lead to irreversible changes in peripheral nerves and skeletal muscle tissue in 4 to 6 hours. The most frequently diseased arteries leading to limb ischemia are the femoropopliteal, tibial, aortoiliac, and brachiocephalic. The common femoral and popliteal arteries are the most common sites of arterial embolism. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1143140224 ER -