TY  - CHAP
M1  - Book, Section
TI  - Sepsis
A1  - Gough, John E.
A2  - Cydulka, Rita K.
A2  - Fitch, Michael T.
A2  - Joing, Scott A.
A2  - Wang, Vincent J.
A2  - Cline, David M.
A2  - Ma, O. John
PY  - 2017
T2  - Tintinalli's Emergency Medicine Manual, 8e
AB  - Sepsis  is  generally  defined  as  a  suspected  or  confirmed  infection  with  evidence  of  systemic  inflammation.  Severe  sepsis  is  sepsis  with  evidence  of  new  organ  dysfunction  thought  to  be  secondary  to  tissue  hypoperfusion.  Septic  shock  is  present  when  cardiovascular  failure  occurs,  reflected  by  persistent  hypotension  or  the  need  for  vasopressors  despite  adequate  fluid  resuscitation.  The  majority  of  sepsis  cases  are  caused  by  gram-negative  and  gram-positive  bacteria;  however,  sepsis  is  a  heterogeneous  clinical  syndrome  that  can  be  caused  by  any  class  of  microorganism  including  fungi,  mycobacteria,  viruses,  rickettsiae,  and  protozoa.  The  most  likely  microorganisms  that  cause  sepsis  varies  based  on  possible  patient  exposure  to  drug-resistant  microorganisms  (e.g.,  due  to  recent  hospitalization  or  other  health  care–associated  exposure)  and  the  specific  anatomic  site  of  suspected  infection.  Pneumonia,  intraabdominal  infection,  urinary  tract  infection,  and  skin  or  soft  tissue  infections  are  the  most  common  infections  that  precipitate  sepsis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessemergencymedicine.mhmedical.com/content.aspx?aid=1143142204
ER  -