TY - CHAP M1 - Book, Section TI - Aspirin A1 - Sivilotti, Marco L. A. A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert PY - 2019 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - Salicylate poisoning is difficult to treat, and consultation with a medical toxicologist is recommended.Children with aspirin toxicity can rapidly develop metabolic acidosis without an apparent respiratory alkalosis.Initial treatment decisions should be predicated on mental status, tachypnea, symptoms such as hearing distortion and blood gases rather than waiting for a serum salicylate concentration.Treatment of mild-to-moderate aspirin poisoning consists of slowing ongoing absorption, correcting volume and electrolyte deficits, alkalinizing the urine, and frequent clinical and laboratory reassessments.Severe aspirin poisoning requires immediate fluid resuscitation, titrated bicarbonate infusion, and emergency hemodialysis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1155748586 ER -