TY - CHAP M1 - Book, Section TI - Opioids A1 - Thompson, Trevonne M. A1 - Erickson, Timothy B. A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert PY - 2019 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - Opioid toxicity is characterized by the classic triad of central nervous system depression, respiratory depression, and miosis.Some opioids, such as methadone, can have prolonged clinical effects.Some opioids—propoxyphene, meperidine, tramadol—can precipitate seizures.Supportive care and the use of naloxone are the mainstays of management. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1155748647 ER -