TY - CHAP M1 - Book, Section TI - Methotrexate, 5-Fluorouracil, and Capecitabine A1 - Wang, Richard Y. A2 - Nelson, Lewis S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Smith, Silas W. A2 - Goldfrank, Lewis R. A2 - Hoffman, Robert S. PY - 2019 T2 - Goldfrank's Toxicologic Emergencies, 11e AB - Methotrexate and the fluoropyrimidines (5-fluorouracil and capecitabine) belong to the chemotherapeutic class of antimetabolites. Patients affected by these chemotherapeutics present with significant clinical toxicities that are potentially fatal. Clinicians must recognize these patients early and be prepared to provide immediate interventions that include specific antidotal therapies. The oral formulations of methotrexate and capecitabine present a risk for intentional or unintentional chemotherapeutics ingestion in the home. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1163012260 ER -