TY - CHAP M1 - Book, Section TI - Melanoma A1 - Hardin, J. Matthew A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Melanoma is a potentially fatal cutaneous tumor derived from epidermal melanocytes. Any age can be affected; peak incidence is in 20- to 45-year-old patients (much younger than BCC or SCC). The most significant risk factor is a primary relative with melanoma. Evaluation of any pigmented lesion should include the ABCDE rule (A for asymmetry, B for irregular borders, C for color variegation, D for diameter > 6 mm, and E for elevation and evolving). Any lesion with these characteristics is considered suspicious for melanoma. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/11/07 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181043999 ER -