TY - CHAP M1 - Book, Section TI - Vancomycin-Induced Red Man Syndrome A1 - Williams, Saralyn R. A1 - Thurman, R. Jason A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Vancomycin has activity against gram-positive bacteria with little to no activity against gram-negative bacteria or mycobacteria. It is poorly absorbed after oral administration, although it may be used orally for treatment of pseudomembranous colitis. Intravenous administration is the most common route. This is well tolerated with minimal burning at the site of the intravenous line; however, rapid infusion may occasionally cause degranulation of mast cells and basophils. As a result, the patient experiences erythematous flushing, particularly of the face and neck, hence the name “red man syndrome.” Tachycardia and hypotension may occasionally be seen. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181056901 ER -