TY - CHAP M1 - Book, Section TI - Neutrophil-Mediated Diseases A1 - Saavedra, Arturo P. A1 - Roh, Ellen K. A1 - Mikailov, Anar PY - 2023 T2 - Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology, 9e AB - PG is an idiopathic, either acute or chronic, severely debilitating skin disease.It is characterized by neutrophilic infiltration, destruction of tissue, and ulceration.It occurs most commonly in association with a systemic disease, especially arthritis, inflammatory bowel disease, hematologic dyscrasias, and malignancy, but may also occur alone.Characterized by the presence of painful, irregular, boggy, blue–red ulcers with undermined borders and purulent necrotic bases.It is a diagnosis of exclusion.The mainstays of treatment are immunosuppressive or immunomodulating agents.Relapses occur in most patients and there is significant morbidity. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/16 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1199569049 ER -