TY - CHAP M1 - Book, Section TI - Chapter 132. Adrenal Insufficiency and Adrenal Crisis A1 - Kefer, Michael P. A2 - Cline, David M. A2 - Ma, O. John A2 - Cydulka, Rita K. A2 - Meckler, Garth D. A2 - Handel, Daniel A. A2 - Thomas, Stephen H. PY - 2012 T2 - Tintinalli's Emergency Medicine Manual, 7e AB - Adrenal insufficiency results when the physiologic demand for glucocorticoids and mineralocorticoids exceeds the supply from the adrenal cortex. The pituitary secretes adrenocorticotropin hormone (ACTH) and associated melanocyte stimulating hormone (MSH). ACTH stimulates the adrenal cortex to secrete cortisol. Cortisol has negative feedback on the pituitary to inhibit secretion of ACTH and MSH. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=56277940 ER -