TY - CHAP M1 - Book, Section TI - Chapter 38. Infectious Endocarditis A1 - Shiber, Joseph R. A2 - Farcy, David A. A2 - Chiu, William C. A2 - Flaxman, Alex A2 - Marshall, John P. PY - 2012 T2 - Critical Care Emergency Medicine AB - Endocarditis, inflammation of the endocardial surface of the heart, can have numerous etiologies including mechanical irritation, neoplastic, autoimmune, or infectious diseases.1–4 This chapter will focus on the infectious causes that are typically bacteria, mycobacteria, and fungi. Although the cardiac valves are most commonly involved, the mural endocardium, septal defects, chordae tendineae, and even intracardiac medical equipment (pacemaker/defibrillator leads or septal occluder devices) can also be sites of infection.1–6 Infectious endocarditis (IE) has an incidence of 3.6/100,000 per year and accounts for 1/1,000 hospital admissions in the United States. There is a 2:1 male to female ratio with current overall in-patient mortality between 11% and 26%, although this figure may be drastically different for the various subsets of IE patients.1,3,7 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=55814558 ER -