TY - CHAP M1 - Book, Section TI - Digoxin A1 - Nelson, Michael E. A2 - Sherman, Scott C. A2 - Weber, Joseph M. A2 - Schindlbeck, Michael A. A2 - Rahul G., Patwari PY - 2014 T2 - Clinical Emergency Medicine AB - Attempt to distinguish between acute versus chronic ingestions, as the symptoms and treatments differ.Electrocardiogram changes are common and include downward-sloping (scooped) ST-segment depressions, premature ventricular complexes, supraventricular dysrhythmias with slow ventricular rates, and bidirectional ventricular tachycardia.Although hyperkalemia can be a marker of significant digoxin poisoning, standard treatment with intravenous calcium should typically be avoided.Empirically administer digoxin-specific antibodies (5 vials for chronic toxicity, 10–20 vials for acute ingestions) to all patients with life-threatening dysrhythmias or hemodynamic instability. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/06 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1101225955 ER -