TY - CHAP M1 - Book, Section TI - High-Altitude Illness A1 - Blumen, Ira J. A1 - Ahn, James A2 - Schafermeyer, Robert A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. PY - 2014 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 4e AB - High-altitude illness (HAI) often affects young and otherwise healthy individuals. It progresses from acute mountain sickness (AMS) to potentially life-threatening high-altitude pulmonary edema (HAPE) and high-altitude cerebral edema (HACE).Acetazolamide (Diamox) has been shown to be very effective for acclimatization when staging is not possible or with individuals who are at an increased risk of HAI.Definitive treatment of HACE is descent. High-flow oxygen is indicated as soon as symptoms are recognized and dexamethasone, at an initial dose of 1 to 2 mg/kg orally or intramuscularly, can produce dramatic improvement.HAPE is the leading cause of high-altitude death other than trauma. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/06 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1105687864 ER -