TY - CHAP M1 - Book, Section TI - NEUTROPHIL-MEDIATED DISEASES A1 - Wolff, Klaus A1 - Johnson, Richard Allen A1 - Saavedra, Arturo P. A1 - Roh, Ellen K. Y1 - 2017 N1 - T2 - Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology, 8e AB - PG is an idiopathic, either acute or chronic, severely debilitating skin disease.It is characterized by neutrophilic infiltration, destruction of tissue, and ulceration.It occurs most commonly in association with a systemic disease, especially arthritis, inflammatory bowel disease, hematologic dyscrasias, and malignancy, but may also occur alone.Characterized by the presence of painful, irregular, boggy, blue-red ulcers with undermined borders and purulent necrotic bases.There is no laboratory test that establishes the diagnosis.The mainstays of treatment are immune-suppressive or -modulating agents.Relapses occur in most patients and there is significant morbidity. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1140789521 ER -