TY - CHAP M1 - Book, Section TI - Psychopharmacologic Agents A1 - Yin, Shan A2 - Cydulka, Rita K. A2 - Fitch, Michael T. A2 - Joing, Scott A. A2 - Wang, Vincent J. A2 - Cline, David M. A2 - Ma, O. John Y1 - 2017 N1 - T2 - Tintinalli's Emergency Medicine Manual, 8e AB - Cyclic antidepressants inhibit reuptake of norepinephrine and serotonin, block sodium channels, and antagonize postsynaptic serotonin receptors. They can produce severe toxicity in overdose. Their use has declined as newer, safer agents have been developed. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1143142684 ER -