TY  - CHAP
M1  - Book, Section
TI  - Alcohols
A1  - Nelson, Michael E.
A1  - Erickson, Timothy B.
A2  - Tenenbein, Milton
A2  - Macias, Charles G.
A2  - Sharieff, Ghazala Q.
A2  - Yamamoto, Loren G.
A2  - Schafermeyer, Robert
Y1  - 2019
N1  - 
T2  - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e
AB  - Ethanol  overdose  in  children  may  result  in  altered  mental  status  and  hypoglycemia.Methanol  poisoning  is  manifested  by  metabolic  acidosis,  visual  disturbance,  and  potential  multiorgan  system  failure.Ethylene  glycol  poisoning  is  manifested  by  metabolic  acidosis,  renal  failure,  and  potential  multiorgan  system  failure.Isopropanol  may  cause  central  nervous  system  (CNS)  depression  and  hypotension  but  does  not  cause  metabolic  acidosis.All  alcohols  can  produce  an  osmolar  gap  but  the  absence  of  an  osmolar  gap  does  not  exclude  a  toxic  alcohol  ingestion.Fomepizole  is  the  only  Food  and  Drug  Administration  (FDA)-approved  antidote  for  ethylene  glycol  and  methanol  poisoning,  and  it  should  be  initiated  if  there  is  strong  clinical  concern  for  ingestion  of  a  toxic  dose  of  these  two  poisons.Hemodialysis  is  indicated  for  toxic  alcohol  poisoning  not  responsive  to  supportive  and  antidote  therapy  or  in  patients  with  evidence  of  end-organ  damage  or  severe  acidosis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessemergencymedicine.mhmedical.com/content.aspx?aid=1155749120
ER  -