TY - CHAP M1 - Book, Section TI - Organophosphates and Carbamates A1 - Gussow, Leon A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert Y1 - 2019 N1 - T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - Organophosphate and carbamate insecticides inactivate the enzyme acetylcholinesterase producing a cholinergic crisis, with the immediate threat to life being respiratory failure.The diagnosis of organophosphate or carbamate poisoning is clinical, with the history of exposure being key; the combination of miosis and increased salivation is relatively specific.Immediate administration of adequate doses of atropine can be life-saving.Pralidoxime is an adjunctive antidote for organophosphate but not for carbamate poisoning. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/07 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1155749405 ER -