TY  - CHAP
M1  - Book, Section
TI  - Systemic Lupus Erythematosus
A1  - Bongartz, Timothy
A1  - Dingle, Jodi A.
A2  - Knoop, Kevin J.
A2  - Stack, Lawrence B.
A2  - Storrow, Alan B.
A2  - Thurman, R. Jason
Y1  - 2021
N1  - 
T2  - The Atlas of Emergency Medicine, 5e
AB  - Systemic  lupus  erythematosus  (SLE)  is  an  autoimmune  disease  that  can  affect  any  organ.  It  is  nine  times  more  common  among  woman,  typically  occurring  during  the  reproductive  years.  The  most  common  manifestations  include  constitutional  symptoms,  skin  rash,  oral  ulcers,  polyarthralgias/arthritis,  and  renal  and  central  nervous  system  involvement.  In  addition,  there  is  a  high  prevalence  of  antiphospholipid  antibodies  among  patients  with  SLE,  resulting  in  hypercoagulability  with  an  increased  risk  of  deep  vein  thrombosis  and  pulmonary  embolism.  Patients  with  SLE  are  at  significant  risk  for  cardiovascular  complications  including  ischemic  stroke  and  myocardial  infarction.  In  fact,  the  most  common  cause  of  premature  death  in  patients  with  SLE  is  accelerated  atherosclerosis.  
SN  - 
PB  - McGraw-Hill
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181053115
ER  -