TY - CHAP M1 - Book, Section TI - Chapter 33. Adrenal Insufficiency A1 - Chiu, William A1 - Marcolini, Evie A1 - Chiu, William C. A2 - Farcy, David A. A2 - Chiu, William C. A2 - Flaxman, Alex A2 - Marshall, John P. Y1 - 2012 N1 - T2 - Critical Care Emergency Medicine AB - Adrenal gland function has provided great academic material for investigation and controversy. It was not until 1937 that 17-hydroxy-11-dehydrocorticosterone, or cortisone, was isolated by Reichstein from the adrenal cortex. By 1947, synthetic cortisone was developed. At the same time, in addition to the use of cortisone for Addison's disease, this compound was found to have a therapeutic effect in patients with rheumatoid pain through its ability to inhibit stress and inflammation. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=55813981 ER -