TY - CHAP M1 - Book, Section TI - Chapter 36. Sepsis and Septic Shock A1 - Farcy, David A. A1 - Yashou, John A1 - Rivers, Emanuel A2 - Farcy, David A. A2 - Chiu, William C. A2 - Flaxman, Alex A2 - Marshall, John P. Y1 - 2012 N1 - T2 - Critical Care Emergency Medicine AB - Of the 120 million patients presenting to the emergency department (ED) in the United States per year, 2.9% or over 600,000 carry a diagnosis of severe sepsis and septic shock in the United States. The overall hospital mortality for sepsis, severe sepsis, and septic shock is 15%, 20%, and 45%, respectively. Sepsis is responsible for 9% of the deaths or 210,000 deaths per year in the United States. By comparison, 180,000 persons die of acute myocardial infarction and 200,000 die of lung or breast cancer annually. Many patients with severe sepsis and septic shock present to the ED where there are often long delays before transfer to an intensive care unit (ICU) bed. Sepsis is the most expensive diagnosis admitted to hospitals accounting for over $50 billion in health care costs each year. It is because of these aforementioned factors that the ED has become a logical focal point for sepsis diagnosis and treatment. It is during the first 6 hours that sepsis management can improve outcomes in one of every six patients who present with the disease.1 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/11/08 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=55814275 ER -