TY - CHAP M1 - Book, Section TI - Chapter 50. Therapeutic Hypothermia: History, Data, Translation, and Emergency Department Application A1 - Gaieski, David F. A1 - Goyal, Munish A2 - Farcy, David A. A2 - Chiu, William C. A2 - Flaxman, Alex A2 - Marshall, John P. Y1 - 2012 N1 - T2 - Critical Care Emergency Medicine AB - Therapeutic hypothermia (TH) has become standard of care for the management of comatose patients with return of spontaneous circulation (ROSC) after cardiac arrest. The 2010 American Heart Association (AHA) guidelines for management of post–cardiac arrest patients “recommend that comatose (i.e., lack of meaningful response to verbal commands) adult patients with ROSC after out-of-hospital ventricular fibrillation (VF) cardiac arrest should be cooled to 32°C to 34°C (89.6°F to 93.2°F) for 12 to 24 hours (Class I, LOE B). Induced hypothermia also may be considered for comatose adult patients with ROSC after in-hospital cardiac arrest of any initial rhythm or after out-of-hospital cardiac arrest with an initial rhythm of pulseless electric activity or asystole (Class IIb, LOE B).”1 Very few recommendations in the AHA guidelines are assigned a Class I recommendation, and, as practitioners at the portal of entry for the majority of cardiac arrest patients, emergency physicians (EPs) need to be familiar with this therapy and the rationale for the level of recommendation assigned to TH. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=55816193 ER -