TY - CHAP M1 - Book, Section TI - Salicylate Toxicity A1 - Aks, Steven E. A2 - Sherman, Scott C. A2 - Weber, Joseph M. A2 - Schindlbeck, Michael A. A2 - Rahul G., Patwari Y1 - 2014 N1 - T2 - Clinical Emergency Medicine AB - Salicylate toxicity causes a mixed respiratory alkalosis, metabolic alkalosis, and elevated anion gap metabolic acidosis.Chronically intoxicated patients will be more seriously ill at lower salicylate concentrations than their acutely poisoned counterparts.Pursue hemodialysis in patients with refractory acidosis, pulmonary edema, renal insufficiency, and altered mental status or seizure, regardless of the actual serum salicylate level.Match the ventilation rate in intubated patients with severe salicylate poisoning to their pre–intubation minute ventilation, as most require remarkably high rates for adequate respiratory compensation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/09/10 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1101225885 ER -