TY - CHAP M1 - Book, Section TI - Psychoses A1 - Tobias, Adam Z. A2 - Tintinalli, Judith E. A2 - Stapczynski, J. Stephan A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Cline, David M. PY - 2016 T2 - Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e AB - Psychosis has been defined as a "fundamental derangement of the mind characterized by defective or lost contact with reality."1 The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V),2 defines psychotic disorders as those that include abnormalities in one or more of five domains: hallucinations, delusions, disorganized or abnormal motor behavior, disorganized thinking, and negative symptoms. The hallmark of these psychoses, schizophrenia, has a worldwide prevalence of 0.5% to 1%3 and affects approximately 2.4 million adults in the United States.4 Considered one of the leading causes of chronic incapacity, the term schizophrenia, meaning "split mind," was coined by Eugene Bleuler in 1911.5 The economic burden of schizophrenia in the United States in 2002 was estimated at $62.7 billion6 and typically accounts for 1.5% to 3% of the total national healthcare expenditure, with a high incidence of ED utilization.7 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1121519213 ER -