TY - CHAP M1 - Book, Section TI - Acute Liver Failure A1 - Hsu, Cindy H. A1 - Menne, Ashley R. A1 - Tisherman, Samuel A. A2 - Farcy, David A. A2 - Chiu, William C. A2 - Marshall, John P. A2 - Osborn, Tiffany M. PY - 2016 T2 - Critical Care Emergency Medicine, 2e AB - Regardless of etiology, the unifying feature of acute liver failure (ALF) is a rapid, often precipitous, clinical course. Whereas spontaneous recovery of liver function is possible with supportive measures, particularly with acetaminophen overdose, there remains a significant risk of spiraling decline after presentation with multi-organ dysfunction, bleeding, and infectious complications often heralded by high-grade encephalopathy with cerebral edema.1 A patient who presents emergently with ALF has an overall greater likelihood of either dying or requiring emergent orthotopic liver transplantation (OLT) than recovering without transplant.2 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1135701416 ER -