TY - CHAP M1 - Book, Section TI - Therapeutic Hypothermia Targeted Temperature Management: History, Data, Translation, and Emergency Department Application A1 - Gaieski, David F. A1 - Goyal, Munish A2 - Farcy, David A. A2 - Chiu, William C. A2 - Marshall, John P. A2 - Osborn, Tiffany M. PY - 2016 T2 - Critical Care Emergency Medicine, 2e AB - Targeted temperature management (TTM), also known as therapeutic hypothermia (TH), has become standard of care for the management of comatose patients with return of spontaneous circulation (ROSC) after cardiac arrest. The 2010 American Heart Association (AHA) guidelines for management of post–cardiac arrest patients recommend that comatose (i.e., lack of meaningful response to verbal commands) adult patients with ROSC after out-of-hospital ventricular fibrillation (VF) cardiac arrest should be cooled to 32°C to 34°C (89.6°F to 93.2°F) for 12 to 24 hours (Class I, LOE B). Induced hypothermia also may be considered for comatose adult patients with ROSC after in-hospital cardiac arrest of any initial rhythm or after out-of-hospital cardiac arrest with an initial rhythm of pulseless electric activity or asystole (Class IIb, LOE B).1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1135704116 ER -