TY - CHAP M1 - Book, Section TI - Evaluation and Management of the Immunocompromised Patient A1 - Cruz, Andrea T. A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert PY - 2019 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - Fever in the immunocompromised child is a medical emergency. Prompt evaluation and administration of antibiotics can decrease morbidity and mortality.Patients on chronic corticosteroids may also require stress dose steroids when febrile.Children with B cell immunodeficiencies are at risk for encapsulated pathogens. Children with T cell defects may present with chronic or severe viral infections, Pneumocystis jirovecii pneumonia, and recurrent bacterial infections.Children with phagocyte defects present with recurrent infections caused by pyogenic bacteria.Children with complement deficiencies present with encapsulated and pyogenic pathogens.Acute HIV infection should be suspected in the adolescent with fever, malaise, diffuse lymphadenopathy, pharyngitis, oral ulcers, and a maculopapular rash. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/18 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1155298005 ER -