TY  - CHAP
M1  - Book, Section
TI  - Oncologic Emergencies
A1  - Wickiser, Jonathan E.
A2  - Tenenbein, Milton
A2  - Macias, Charles G.
A2  - Sharieff, Ghazala Q.
A2  - Yamamoto, Loren G.
A2  - Schafermeyer, Robert
PY  - 2019
T2  - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e
AB  - Acute  leukemia  is  the  most  common  malignancy  in  childhood  and  may  present  with  a  variety  of  symptoms  including  fever,  fatigue,  bleeding,  adenopathy,  or  bone  pain.Most  oncologic  emergencies  arise  from  metabolic,  hematologic,  structural,  or  toxic  chemotherapy  effects.Findings  associated  with  inflammation  may  be  absent  in  the  immunocompromised  patient,  with  fever  potentially  the  only  sign  of  serious  infection.  However,  immunocompromised  patients  may  have  serious  infections  without  the  presence  of  fever.Infection  may  progress  rapidly  in  the  immunocompromised  host;  evaluation  and  initiation  of  antibiotic  therapy  must  be  done  urgently.Tumor  lysis  syndrome  (TLS)  results  from  the  death  of  tumor  cells  and  release  of  their  intracellular  contents  leading  to  hyperuricemia,  hyperphosphatemia,  and  hyperkalemia.Mediastinal  compression  from  tumor  may  result  in  superior  vena  cava  syndrome  (SVCS)  or  superior  mediastinal  syndrome  (SMS),  resulting  in  an  airway  emergency.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessemergencymedicine.mhmedical.com/content.aspx?aid=1155748284
ER  -