TY - CHAP M1 - Book, Section TI - Subcutaneous Hydration (Hypodermoclysis) A1 - J. O, Mary A2 - Reichman, Eric F. PY - 2018 T2 - Reichman's Emergency Medicine Procedures, 3e AB - Subcutaneous rehydration therapy (SCRT), also known as hypodermoclysis, is a method of fluid replacement first described in the 1880s as a proposed treatment for cholera in India.1 It involves the infusion of fluids into the subcutaneous space where it slowly diffuses into the circulation.2 This method was widely used for rehydration until the 1950s until it was superseded by the intravenous (IV) route.3 This was due to reports of serious adverse events that were most likely caused by improper choice of fluids for SCRT (e.g., shock secondary to osmotic shift caused by infusion of hypertonic or electrolyte-free fluids).4 Subsequent studies have confirmed the safety and efficacy of hypodermoclysis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1159804242 ER -