TY - CHAP M1 - Book, Section TI - Plantar Wart Management A1 - O’Rourke, Kevin A2 - Reichman, Eric F. PY - 2018 T2 - Reichman's Emergency Medicine Procedures, 3e AB - Plantar warts (i.e., verruca pedis) are caused by infection of the epidermal skin layer with the human papillomavirus (HPV). Plantar warts were discussed as far back as the ancient Greeks and Romans. They were subsequently identified as being caused by infectious agents in the late 1800s. HPV, a member of the Papovaviridae family, was identified in 1949 and is composed of double-stranded DNA. The peak incidence of plantar warts occurs in the teenage years.1 They are estimated to occur in 10% of children and young adults, with a greater prevalence in females. HPV enters the host keratinocyte through an epidermal abrasion with the help of a transiently impaired immune system. It is found in the upper epidermis and results in squamous epithelial cell hyperplasia. Numerous types of HPV exist. Simple plantar warts are mainly due to HPV types 1, 2, 4, 27, or 57. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1159810481 ER -