TY  - CHAP
M1  - Book, Section
TI  - Benzodiazepines
A1  - Horner, Fiona Garlich
A1  - Hoffman, Robert S.
A1  - Nelson, Lewis S.
A1  - Howland, Mary Ann
A2  - Nelson, Lewis S.
A2  - Howland, Mary Ann
A2  - Lewin, Neal A.
A2  - Smith, Silas W.
A2  - Goldfrank, Lewis R.
A2  - Hoffman, Robert S.
PY  - 2019
T2  - Goldfrank's Toxicologic Emergencies, 11e
AB  - Benzodiazepines  are  a  class  of  sedative–hypnotics  that  share  similar  chemical  structures,  receptor  physiology,  and  clinical  effects.  Benzodiazepines  are  used  broadly  for  a  range  of  clinical  indications,  including  xenobiotic-induced  seizures,  xenobiotic-induced  psychomotor  agitation,  withdrawal  from  ethanol  and  other  sedative–hypnotics,  cocaine-associated  myocardial  ischemia,  chloroquine  overdose,  and  to  induce  muscle  relaxation  in  serotonin  toxicity,  neuroleptic  malignant  syndrome,  strychnine  poisoning,  and  black  widow  spider  envenomation.  This  Antidotes  in  Depth  provides  a  summary  of  the  clinical  pharmacology  of  benzodiazepines  and  a  review  of  their  use  in  ­specific  clinical  scenarios,  with  an  emphasis  on  specific  drug  selection  and  safe  administration.  A  discussion  of  the  manifestations  and  treatment  of  overdose  of  benzodiazepines  and  similar  xenobiotics  is  found  in  Chap.  72.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessemergencymedicine.mhmedical.com/content.aspx?aid=1163003019
ER  -