TY - CHAP M1 - Book, Section TI - High-Altitude Cerebral Edema A1 - Zafren, Ken A1 - Thurman, R. Jason A1 - Jones, Ian D. A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Acute mountain sickness (AMS) is a symptom complex that usually begins 12 to 24 hours after ascent to high altitude and consists of headache and one or more other symptoms, including gastrointestinal symptoms, fatigue and/or weakness, dizziness and/or lightheadedness, and difficulty sleeping. High-altitude cerebral edema (HACE) is a severe form of AMS, clinically defined by the presence of acute truncal ataxia, altered mental status, or both. Usually this occurs as a progression from AMS to HACE, but HACE may occur without antecedent AMS. If not effectively treated, HACE may progress to coma or death. Focal neurologic findings other than truncal ataxia are rare and should suggest another diagnosis, such as acute stroke or venous sinus thrombosis. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/04/20 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181050805 ER -