TY - CHAP M1 - Book, Section TI - Cardiac Glycoside Plant Ingestion A1 - Williams, Saralyn R. A1 - Thurman, R. Jason A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Cardiac glycosides (CGs) are found in the leaves, flowers, and seeds of Nerium oleander (common oleander), Thevetia peruviana (yellow oleander), Digitalis purpurea (foxglove), Strophanthus gratus (ouabain), Convallaria majalis (lily of the valley), Apocynum cannabinum (dogbane), Urginea maritima and Urginea indica (squill), and Cheiranthus cheiri (wallflower). If ingested, they produce clinical findings similar to digoxin toxicity. The drinking of foxglove and oleander tea may be a cause of CG toxicity. Therapeutic effects occur from inhibition of the cardiac cell membrane sodium-potassium ATP pump, resulting in increased automaticity, decreased conduction through the atrioventricular node, and improved inotropy. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181057117 ER -