TY - CHAP M1 - Book, Section TI - Kaposi Sarcoma A1 - Raffanti, Stephen P. A1 - Person, Anna K. A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Kaposi sarcoma (KS) is a low-grade vascular tumor associated with human herpesvirus 8 (HHV-8). Since the introduction of highly active antiretroviral therapy (HAART), the incidence of KS in HIV-infected persons has significantly declined. Skin involvement is characteristic, but extracutaneous spread of KS is common, particularly to the oral cavity, gastrointestinal (GI) tract, and respiratory tract. The skin lesions appear most often on the lower extremities, face (especially the nose), oral mucosa, and genitalia. Most commonly, the lesions are papular, ranging in size from several millimeters to centimeters in diameter. Less commonly, the lesions may be plaque-like, especially on the soles of the feet, or exophytic and fungating with breakdown of overlying skin. Papular lesions may resemble lesions associated with bacillary angiomatosis or herpesvirus infections. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/04/19 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181057357 ER -