TY - CHAP M1 - Book, Section TI - Herpes Simplex Virus A1 - Raffanti, Stephen P. A1 - Person, Anna K. A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Infection with herpes simplex virus (HSV) is extremely common in HIV-infected patients and may present with oral, genital, anal, esophageal, or ophthalmologic involvement. The hallmark for most clinical presentations of HSV outbreaks is an inflammatory cutaneous eruption, with or without vesicles, and pain. HSV esophagitis is seen in immunocompromised HIV-infected patients and presents as dysphagia and odynophagia with or without oral lesions. Idiopathic aphthous ulcerations in HIV-infected patients are indistinguishable from HSV lesions. Perirectal lesions are often erythematous, ulcerative, and extremely tender, with a predilection for the gluteal cleft. Perirectal HSV may also be associated with proctitis and anal fissures. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/04/18 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1181057439 ER -